Facial asymmetry with nasal and orbital involvement in a case of sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease)
✍ Scribed by Omar A. El-Banhawy; Hassan G. Farahat; Ibrahiem El-Desoky
- Book ID
- 116563896
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 194 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0165-5876
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Sinus histiocytosis with massive lymphadenopathy (SHML) is a rare entity characterized by the prolifration of cells belonging to the macrophage-histiocyte family, but whose exact origin is unknown. A case of SHML occurring in a 62-yr-old female is described in which the diagnosis is initially sugges
## Sinus histiocytosis with massive lymphadenopathy (SHML) is a benign, self-limiting condition of unknown etiology, which generally presents as massive bilateral cervical lymphadenopathy. It is important to distinguish SHML from other causes of histiocytosis because of the different treatment modal
Langerhans' cell histiocytosis (LCH) is a clonal proliferation of Langerhans cells (LC) showing histologically an abundant reactive infiltrate composed of macrophages and lymphocytes, as well as eosinophilic and neutrophilic granulocytes. Rosai-Dorfman disease (RDD) shows a sinusoidal accumulation o