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F.125. Systemic Tumor Immunity Requires Distinctive Immune Responses Between CD4+ and CD8+ T Lymphocytes Against a Tumor Specific Antigen

✍ Scribed by Devin Lowe; Michael Shearer; Cynthia Jumper; Ronald Kennedy


Book ID
116366546
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
55 KB
Volume
119
Category
Article
ISSN
1090-2341

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Dendritic cells (DCs) are potent inducers of cytotoxic T lymphocytes (CTLs) when pulsed with an antigenic peptide or tumor lysate. In this report, we have used liposomemediated gene transfer to examine the ability of plasmid DNA encoding the human melanoma-associated antigen gp100 to elicit CD8 Ψ‰ an