## Abstract Spontaneous tumors frequently express antigens that can be recognized by the immune system but nevertheless manage to evade immune surveillance. To better understand the mechanism of evasion, we followed CD8 and CD4 T cells reacting against a subcutaneously growing tumor, modified to ex
Regulatory balance between the immune response of tumor antigen-specific T-cell receptor gene-transduced CD8+ T cells and the suppressive effects of tolerogenic dendritic cells
β Scribed by Shin-ichiro Fujii; Michael I. Nishimura; Michael T. Lotze
- Book ID
- 108583565
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 215 KB
- Volume
- 96
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Chronicity of hepatitis B virus (HBV ) infection is characterized by a weak immune response to the virus. CD4 Ψ CD25 Ψ regulatory T cells (Treg) are present in increased numbers in the peripheral blood of chronic HBV patients, and these Treg are capable of suppressing the HBV-specific immune re
The sensitivity of immature thymocytes to antigen-induced deletion has been shown to correlate with their differentiation status. By using an in vitro approach we have investigated whether parameters of antigenic stimulation may also affect the response of thymocytes. Two T cell receptor (TcR)-trans