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Extrathymic T-cell differentiation in vitro

✍ Scribed by Pawelec, Graham


Book ID
109953963
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
53 KB
Volume
4
Category
Article
ISSN
1474-1741

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The T-cell repertoire is formed during T lymphocyte maturation in the thymus. There is, however, increasing evidence that there are additions to, and modifications of, this repertoire by extrathymic events. Most importantly, mature peripheral T cells are not only susceptible to activation signals bu