Extrathymic T-cell selection
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Bernd Arnold; GΓΌnther SchΓΆnrich; GΓΌnter J. HΓ€mmerling
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Article
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1992
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Elsevier Science
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English
β 639 KB
The T-cell repertoire is formed during T lymphocyte maturation in the thymus. There is, however, increasing evidence that there are additions to, and modifications of, this repertoire by extrathymic events. Most importantly, mature peripheral T cells are not only susceptible to activation signals bu