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External proofreading of DNA replication errors and mammalian autonomous 3′ → 5′ exonucleases

✍ Scribed by I.V. Shevelev; T.P. Kravetskaya; O.K. Legina; V.M. Krutyakov


Book ID
113194886
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
420 KB
Volume
352
Category
Article
ISSN
0027-5107

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The 3′ → 5′ exonucleases of both DNA pol
✍ Morrison, Alan ;Sugino, Akio 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 832 KB

DNA polymerases II (epsilon) and III (delta) are the only nuclear DNA polymerases known to possess an intrinsic 3'-->5' exonuclease in Saccharomyces cerevisiae. We have investigated the spontaneous mutator phenotypes of DNA polymerase delta and epsilon 3'-->5' exonuclease-deficient mutants, pol3-01