Extensive exercise is not harmful in amyotrophic lateral sclerosis
β Scribed by David Liebetanz; Katrin Hagemann; Friederike Von Lewinski; Elke Kahler; Walter Paulus
- Book ID
- 109020719
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 312 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0953-816X
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π SIMILAR VOLUMES
While both upper and lower motor neuron dysfunction may contribute to impaired muscle function in amyotrophic lateral sclerosis (ALS), the precise mechanisms of muscle fatigue have not been clarified in this disease. Therefore, the central and peripheral factors in muscle fatigue were investigated d
## Abstract We tested whether a regular exercise regimen was associated with a change in the life span of G93AβSOD1 transgenic mice, a model of familial ALS. Regular treadmill running for 10 weeks led to a significant increase in the life span of G93AβSOD1 mice. The effect was stronger in male mice