The design and synthesis of mimetics of
✍
Michael Kahn; Susanne Wilke; Barbara Chen; Kagari Fujita; Yu-Hwei Lee; Michael E
📂
Article
📅
1988
🏛
John Wiley and Sons
🌐
English
⚖ 410 KB
The synthesis of an 11 membered ring bis-lactam, a system which is designed as a conformationally restricted mimetic of type I and type II beta-turns is described. Computer assisted molecular modeling was used to compare the predicted low energy conformers of the turn mimetic with idealized type I a