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ChemInform Abstract: Racemic, Yet Diastereomerically Pure Azido Acids as Both γ-Turn and Inverse γ-Turn Mimetics for Solid-Phase Peptide Synthesis.

✍ Scribed by B. SCHMIDT; C. KUEHN


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: An Approach to Enan
✍ K. BRICKMANN; P. SOMFAI; J. KIHLBERG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB

An Approach to Enantiomerically Pure Inverse γ-Turn Mimetics for Use in Solid-Phase Synthesis. -The carboxyl group of the title mimetic (VII), which corresponds to a Phe-Ala-Ala synthon, may be linked to peptides. Reduction of the azido group renders possible elongation at the N-terminus thus allowi