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ChemInform Abstract: An Approach to Enantiomerically Pure Inverse γ-Turn Mimetics for Use in Solid-Phase Synthesis.

✍ Scribed by K. BRICKMANN; P. SOMFAI; J. KIHLBERG

Publisher: John Wiley and Sons
Year: 2010
Weight: 33 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199734235

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✦ Synopsis

An Approach to Enantiomerically Pure Inverse γ-Turn Mimetics for Use in Solid-Phase Synthesis. -The carboxyl group of the title mimetic (VII), which corresponds to a Phe-Ala-Ala synthon, may be linked to peptides. Reduction of the azido group renders possible elongation at the N-terminus thus allowing its use in solid-phase synthesis. -(BRICKMANN, K.; SOMFAI,

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