Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1a
β Scribed by Hiroshi Wada; Hiroaki Nagano; Hirofumi Yamamoto; Yubo Yang; Motoi Kondo; Hideo Ota; Masato Nakamura; Shinichi Yoshioka; Hitoshi Kato; Bazarragchaa Damdinsuren; Di Tang; Sigeru Marubashi; Atsushi Miyamoto; Yutaka Takeda; Koji Umeshita; Shoji Nakamori; Masato Sakon; Keizo Dono; Kenichi Wakasa; Morito Monden
- Book ID
- 111237485
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 363 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0106-9543
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## Background: Hypoxia-inducible factor 1alpha (hif-1alpha) and hif-2alpha are essential regulatory proteins for the adaptation of tumor cells to hypoxia, and they stimulate angiogenesis through activation of the vascular endothelial growth factor (vegf) gene. ## Methods: Hif-1alpha and hif-2alph