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Relation of hypoxia-inducible factor 1a to angiogenic profile and prognosis in patients with bladder cancer

โœ Scribed by V.E Theodoropoulos; A.C Lazaris; F Sofras; J Gerzelis; A Tsigka; I Ghikonti; K Manikas; J Kastriotis

Book ID
118645057
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
104 KB
Volume
2
Category
Article
ISSN
1569-9056

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## Background: Hypoxia-inducible factor 1alpha (hif-1alpha) and hif-2alpha are essential regulatory proteins for the adaptation of tumor cells to hypoxia, and they stimulate angiogenesis through activation of the vascular endothelial growth factor (vegf) gene. ## Methods: Hif-1alpha and hif-2alph