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Expression of wild type and mutant glutamine synthetase in foreign hosts


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
121 KB
Volume
20
Category
Article
ISSN
0020-711X

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The kinetics and cytidine 5'-triphosphate (CTP) feedback inhibition of CTP synthetase in wild-type and four mutants of Chinese hamster V79 cells have been studied. The enzymes of the wild type and three of the four mutants exhibited positive cooperativity with the substrate uridine 5'-triphosphate (