## Abstract Thrombosis is a major complication and an important cause of death in cancer patients. Tumor cells may trigger coagulation and induce a prothrombotic phenotype, which in return may enhance angiogenesis, tumor growth, and metastasis. Tissue factor pathway inhibitor (TFPI) has been report
Expression and characterization of wild-type TFPI and the [P151L]TFPI mutant in insect cells
✍ Scribed by Elmar Thyzel; Sabine Siegling; Thomas Brinkmann; Knut Kleesiek; Christian Götting
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 200 KB
- Volume
- 283
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Activating __BRAF__ mutations and loss of wild‐type __INK4A__ expression both occur at high frequencies in melanomas. Here, we present evidence that __BRAF__ and __INK4A__ have different effects on melanogenesis, a marker of melanocytic differentiation. Human melanoma cell line 624Mel h
The kinetics and cytidine 5'-triphosphate (CTP) feedback inhibition of CTP synthetase in wild-type and four mutants of Chinese hamster V79 cells have been studied. The enzymes of the wild type and three of the four mutants exhibited positive cooperativity with the substrate uridine 5'-triphosphate (