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Glutamine synthetase (GS) expression is reduced in senile dementia of the Alzheimer type

✍ Scribed by Ghislaine Prince; Pia Delaere; Christiane Fages; Thierry Lefrançois; Monique Touret; Marcelle Salanon; Marcienne Tardy


Publisher
Springer
Year
1995
Tongue
English
Weight
404 KB
Volume
20
Category
Article
ISSN
0364-3190

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Milacemide, both an MAO-B inhibitor and a prodrug for glycine, has demonstrated cognitive enhancing effects in animal models, in cognitively intact young and elderly, and has been suggested as a potential treatment for senile dementia of the Alzheimer type (SDAT). This multicenter open-label trial e