✦ LIBER ✦

Expression of the teratocarcinoma phenotype in hybrids between totipotent mouse teratocarcinoma and myeloma cells

✍ Scribed by Alessandro Correani; Carlo M. Croce

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 645 KB
Volume: 105
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041050110

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We have produced somatic cell hybrids between totipotent mouse teratocarcinoma and myeloma cells. These hybrids behave like the teratocar‐cinoma cell parent and express teratocarcinoma embryonal antigens. However, they also express the myeloma H‐2 antigens. The availability of these hybrids should make it possible to study the expression of already rearranged immunoglobulin genes during mouse development.

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