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Expression of the cyclin kinase inhibitor, p27kip1, in developing and mature human kidney

โœ Scribed by Combs, Heidi L.; Shankland, Stuart J.; Setzer, Shannon V.; Hudkins, Kelly L.; Alpers, Charles E.


Book ID
109065137
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
288 KB
Volume
53
Category
Article
ISSN
0085-2538

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The p27 Kip1 protein is a negative regulator of the cell cycle and a potential tumor suppressor gene. Reduced expression of the p27 Kip1 protein has been reported in several human tumors and has been associated with higher tumor grade and increased mortality in breast, lung, colon, prostate, bladder