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EXPRESSION OF THE CATALYTIC SUBUNIT ASSOCIATED WITH TELOMERASE GENE IN HUMAN URINARY BLADDER CANCER

โœ Scribed by Liu, Brian C.-S.


Book ID
122441953
Publisher
Lippincott Williams and Wilkins
Year
1999
Tongue
English
Weight
42 KB
Volume
162
Category
Article
ISSN
0022-5347

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Hypermethylation of the human telomerase
โœ Isabelle Guilleret; Pu Yan; Fabienne Grange; Richard Braunschweig; Fred T. Bosma ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 443 KB

DNA methylation is an epigenetic process involved in embryonic development, differentiation and aging. It is 1 of the mechanisms resulting in gene silencing in carcinogenesis, especially in tumor suppressor genes (e.g., p16, Rb). Telomerase, the DNA polymerase adding TTAGGG repeats to the chromosome