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Expression of TGF-β type I and II receptors in normal and cancerous human endometrium

✍ Scribed by Dagmara Piestrzeniewicz-Ulanska; Magdalena Brys; Andrzej Semczuk; Jerzy A Jakowicki; Wanda M Krajewska


Book ID
117467483
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
190 KB
Volume
186
Category
Article
ISSN
0304-3835

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Transforming growth factor-b (TGF-b1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investi