𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ

✍ Scribed by Adnane, Jalila; Bizouarn, Francisco A; Chen, Zhi; Ohkanda, Junko; Hamilton, Andrew D; Munoz-Antonia, Teresita; Sebti, Saïd M


Book ID
110064232
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
308 KB
Volume
19
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Transfection of the type I TGF-β recepto
✍ Markus Wagner; Jörg Kleeff; Martha E. Lopez; Irene Bockman; Joan Massaqué; Murra 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 113 KB 👁 1 views

Transforming growth factor-beta (TGF-beta) signaling is initiated following heterodimerization of the type II TGF-beta receptor (TbetaRII) with the type I TGF-beta receptor (TbetaRI). Both receptors are required for TGF-beta responsiveness. In the present study, we characterized the actions of TGF-b

Changes in TGF-β receptors of rat hepato
✍ Yuji Nishikawa; Meifang Wang; Brian I. Carr 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB 👁 1 views

To clarify the role of transforming growth factor-b (TGF-b) and its receptors in hepatocyte growth, we studied the expression of TGF-b1 and its receptors and the sensitivity to growth inhibition by TGF-b1 protein in rat hepatocytes derived from resting and regenerating livers. In hepatocytes derived

Expression of transforming-growth-factor
✍ Ester Piek; Ulrica Westermark; Marianne Kastemar; Carl-Henrik Heldin; E. Joop va 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 268 KB 👁 1 views

A panel of 6 human glioma cell lines was examined for TGF-␤1 responsiveness. U-178 MG and U-251 MG AgCl1 were significantly inhibited by TGF-␤1, while U-343 MGa 31L and U-343 MGa 35L were potently stimulated to proliferate. TGF-␤1 induced endogenous PAI-1 protein synthesis, Smad binding element/(CAG