Transforming growth factor-beta (TGF-beta) signaling is initiated following heterodimerization of the type II TGF-beta receptor (TbetaRII) with the type I TGF-beta receptor (TbetaRI). Both receptors are required for TGF-beta responsiveness. In the present study, we characterized the actions of TGF-b
Inhibition of farnesyltransferase increases TGFβ type II receptor expression and enhances the responsiveness of human cancer cells to TGFβ
✍ Scribed by Adnane, Jalila; Bizouarn, Francisco A; Chen, Zhi; Ohkanda, Junko; Hamilton, Andrew D; Munoz-Antonia, Teresita; Sebti, Saïd M
- Book ID
- 110064232
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 308 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0950-9232
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