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Role of TGF-β1 and TGF-β type II receptor in gastric cancer

✍ Scribed by Ju Sung Kim; Hee Jung Son; Dong Il Park; Sang Yong Song; Won Hyeok Choe; Yun Jeong Lim; Sang-Jong Park; Jae J. Kim; Young-Ho Kim; Poong-Lyul Rhee; Seung Woon Paik; Jong Chul Rhee; Kyoo Wan Choi


Book ID
119391753
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
27 KB
Volume
96
Category
Article
ISSN
0002-9270

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Transforming growth factor-beta (TGF-beta) signaling is initiated following heterodimerization of the type II TGF-beta receptor (TbetaRII) with the type I TGF-beta receptor (TbetaRI). Both receptors are required for TGF-beta responsiveness. In the present study, we characterized the actions of TGF-b