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Expression of p18INK4Cis Down-regulated in Human Pituitary Adenomas

✍ Scribed by Md. Golam Hossain; Takeo Iwata; Noriko Mizusawa; Zhi Rong Qian; Shahidan Wan Nazatul Shima; Toru Okutsu; Shozo Yamada; Toshiaki Sano; Katsuhiko Yoshimoto

Book ID
107571851
Publisher
Springer US
Year
2009
Tongue
English
Weight
380 KB
Volume
20
Category
Article
ISSN
1046-3976

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Cyclins, cyclin-dependent kinases (Cdks), and Cdk inhibitors (CdkIs) are frequently altered in human cancer. p18 INK4C , a member of the INK4 family of CdkIs, is a potential tumorsuppressor gene product. However, the expression of p18 INK4C in hepatocellular carcinoma (HCC) remains unknown. The aim