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Expression of Multidrug Resistance Proteins (Mrps) in Astrocytes of the Mouse Brain: A Single Cell RT-PCR Study

✍ Scribed by Johannes Hirrlinger; Heinz Moeller; Frank Kirchhoff; Ralf Dringen

Publisher: Springer
Year: 2005
Tongue: English
Weight: 289 KB
Volume: 30
Category: Article
ISSN: 0364-3190
DOI: 10.1007/s11064-005-8795-y

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## Abstract Inherent and acquired multidrug resistance (MDR) is characterized by a simultaneous resistance to diverse anticancer drugs and is a major impediment towards curative chemotherapy of cancer. Hence one important goal is to develop strategies aimed at specific targeting of major anticancer