Expression of MT1-MMP during deciduous tooth resorption in odontoclasts
β Scribed by Busayarat Linsuwanont-Santiwong; Yuzo Takagi; Keiichi Ohya; Hitoyata Shimokawa
- Book ID
- 106230921
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 443 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0914-8779
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## Membrane -type 1 matrix metalloproteinase (MT1-MMP) is a presumed activator of MMP2, which is one of the major proteinases in tumor cell invasion. In this study, we determined the clinico-pathologic significance of MT1-MMP expression in 68 human gastric carcinomas. The tumor-normal ratio (T/N r
## Abstract Matrix metalloproteinases (MMPs) are zincβdependent proteases capable of degrading extracellular matrix components. The activity of these proteases is tightly regulated through the actions of the tissue inhibitors of metalloproteinases (TIMPs). Although the regulation of MMPs and TIMPs