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Expression of MDR1 and glutatione S transferase-π genes and chemosensitivities in human gastrointestinal cancer

✍ Scribed by Tetsuya Satta; Ken-Ichi Isobe; Masaji Yamauchi; Izumi Nakashima; Hiroshi Takagi

Book ID: 102669489
Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 557 KB
Volume: 69
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19920215)69:4<941::aid-cncr2820690418>3.0.co;2-h

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## ~ ~~~~ The mRNA expression of mdrl and MRP, each of which codes for a transport protein belonging to ATP-binding cassette superfamily and are reported to be responsible for multidrug resistance phenotype, were semiquantified by RT-PCR in a panel of gastrointestinal cancer cell lines. Although t