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Glutathione S-transferase-π gene expression and platinum drug exposure in human lung cancer

✍ Scribed by Tetsuya Oguri; Yasuhiro Fujiwara; Osamu Katoh; Haruko Daga; Nobuhisa Ishikawa; Kazunori Fujitaka; Masahiro Yamasaki; Michiya Yokozaki; Takeshi Isobe; Shin-ichi Ishioka; Michio Yamakido


Book ID
117466549
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
122 KB
Volume
156
Category
Article
ISSN
0304-3835

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✍ Tetsuya Oguri; Takeshi Isobe; Kazunori Fujitaka; Nobuhisa Ishikawa; Nobuoki Kohn 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 155 KB

To investigate the roles played by the multidrug resistance-associated protein (MRP1) homologues MRP3 and MRP4 in resistance to platinum drugs, we examined steady-state levels of mRNA for both MRP3 and MRP4 in normal lung and lung cancer specimens as well as peripheral mononuclear cells (PMN) after