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Expression of Matrix Metalloproteinase 2 (MMP-2) and Tissue Inhibitor of Metalloproteinase 2 (TIMP-2) in Medullary Thyroid Carcinoma: Prognostic Implications

✍ Scribed by Cavalheiro, Beatriz G.; Junqueira, Consuelo Rodrigues; Brandão, Lenine G.

Book ID: 121800661
Publisher: Mary Ann Liebert
Year: 2008
Tongue: English
Weight: 489 KB
Volume: 18
Category: Article
ISSN: 1050-7256
DOI: 10.1089/thy.2007.0412

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## Background: Matrix metalloproteinase-2 (mmp-2), which degrades the extracellular matrix or the basement membrane, has an essential role in tumor invasion and metastasis. to evaluate the roles of mmp-2, its inhibitor (tissue inhibitor of metalloproteinase-2 [timp-2]), and its activator (membrane-