## Abstract Matrix metalloproteinases (MMPs) degrade the extracellular matrix and are implicated in the pathogenesis of several neurological diseases. Secreted in proforms, the MMPs require activation. Tissue inhibitors of matrix metalloproteinases (TIMPs) regulate the activity of MMPs. We investig
โฆ LIBER โฆ
Matrix metalloproteinase-2 regulates the expression of tissue inhibitor of matrix metalloproteinase-2
โ Scribed by Kaoru Kimura; Xian Wu Cheng; Kae Nakamura; Aiko Inoue; Lina Hu; Haizhen Song; Kenji Okumura; Akihisa Iguchi; Toyoaki Murohara; Masafumi Kuzuya
- Book ID
- 108940757
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 416 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0305-1870
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## Background: Matrix metalloproteinase-2 (mmp-2), which degrades the extracellular matrix or the basement membrane, has an essential role in tumor invasion and metastasis. to evaluate the roles of mmp-2, its inhibitor (tissue inhibitor of metalloproteinase-2 [timp-2]), and its activator (membrane-
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