Expression of JC virus agnoprotein in progressive multifocal leukoencephalopathy brain
β Scribed by Yuki Okada; Hirofumi Sawa; Shuichi Endo; Yasuko Orba; Takashi Umemura; Hiroshi Nishihara; Alexandru C. Stan; Shinya Tanaka; Hidehiro Takahashi; Kazuo Nagashima
- Book ID
- 106072794
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 333 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0001-6322
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## Abstract Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, which is thought to be a result of the reactivation of JC virus (JCV), a human polyomavirus. The disease occurs in individuals with immunosuppression and in recent years there has
## Abstract The kidneys of six progressive multifocal leukoencephalopathy (PML) patients were examined by PCR amplification for the presence of JC virus. Amplification of three different areas of the viral genome from multiple samples of each kidney revealed three that were positive for the virus.