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Expression of hormone-regulated genes in osteoblastic cells with reference to postmenopausal osteoporosis

✍ Scribed by S Reppe; OK Olstad; VT Gautvik; E Rian; R Jemtland; KM Gautvik


Book ID
117807227
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
85 KB
Volume
27
Category
Article
ISSN
8756-3282

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The inositol trisphosphate receptor (IP3R) is an intracellular calcium channel that mediates the cellular actions of a wide variety of hormones, growth factors, and cytokines. In osteoblastic cell cultures, many bone resorbing hormones increase phosphoinositide turnover, inositol trisphosphate produ