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Regulation of Osteoblast Gene Expression in Intratypic Osteosarcoma Hybrid Cells

✍ Scribed by Teresa L. Johnson-Pais; Robin J. Leach

Book ID
115602210
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
584 KB
Volume
221
Category
Article
ISSN
0014-4827

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## Abstract The introduction of systemic chemotherapy improved significantly the prognosis of osteosarcoma. Despite this success, approximately 30–40% of patients will relapse. Cytotoxic drugs have been shown to induce apoptosis in the target cells independent of their primary effects. The underlyi