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Expression of differential immune factors in temporal cortex and cerebellum: The role of α-1-antichymotrypsin, apolipoprotein E, and reactive glia in the progression of Alzheimer's disease

✍ Scribed by Scot D. Styren; M. Ilyas Kamboh; Steven T. Dekosky

Book ID
111697385
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
506 KB
Volume
396
Category
Article
ISSN
0021-9967

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A common polymorphism in the α1-antichymotrypsin (ACT) gene has been found to modify the APOE\*4-associated risk of Alzheimer's disease due to an apparent interaction between the two loci. This study was undertaken to determine the gender-and age-related distributions of these two polymorphisms in t