Connective tissue growth factor (CTGF) stimulates in vitro fibroblast proliferation and extracellular matrix synthesis. The aim of this study was to assess the role of CTGF in liver fibrogenesis. CTGF expression was investigated both at the protein and mRNA level in biopsies of chronic liver disease
β¦ LIBER β¦
Expression of connective tissue growth factor in human renal fibrosis
β Scribed by Ito, Yasuhiko; Aten, Jan; Bende, Richard J.; Oemar, Barry S.; Rabelink, Ton J.; Weening, Jan J.; Goldschmeding, Roel
- Book ID
- 109065118
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 777 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0085-2538
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## Abstract ## Objective Connective tissue growth factor (CTGF) is a cysteineβrich secreted matricellular protein involved in wound healing and tissue repair. Enhanced and prolonged expression of CTGF has been associated with tissue fibrosis in humans. However, questions remain as to whether CTGF
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