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Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

โœ Scribed by Biden, Kelli G; Simms, Lisa A; Cummings, Margaret; Buttenshaw, Ron; Schoch, Estelle; Searle, Jeffrey; Gobe, Glenda; Jass, Jeremy R; Meltzer, Stephen J; Leggett, Barbara A


Book ID
110061865
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
728 KB
Volume
18
Category
Article
ISSN
0950-9232

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Using western blotting and immunochemical analysis, we investigated alterations in the expression of the apoptosis-related proteins bcl-2, bax, and bcl-X in colonic adenocarcinomas induced by subcutaneous injection of azoxymethane (AOM) (15 mg/kg body weight weekly for 2 wk) into male Sprague-Dawley