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Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location

✍ Scribed by So Yeon Park; Hye Seung Lee; Gheeyoung Choe; Jin Haeng Chung; Woo Ho Kim


Publisher
Springer
Year
2006
Tongue
English
Weight
322 KB
Volume
449
Category
Article
ISSN
1432-2307

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Heat shock proteins (hsp) are molecular chaperones that are increased by various environmental and patho-physiological stimuli. Hsp can bind to mutant/wild-type p53 in tumors and, consequently, could not only regulate p53 accumulation or localization but also modulate its biological effects on cells