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Expression and Regulation of Tumor Suppressor Gene Maspin in Breast Cancer

โœ Scribed by Nicolai Maass; Koichi Nagasaki; Martin Ziebart; Christoph Mundhenke; Walter Jonat

Book ID
119934623
Publisher
CIG Media Group, LP.
Year
2002
Tongue
English
Weight
962 KB
Volume
3
Category
Article
ISSN
1526-8209

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Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis; however, its precise role in normal mammary epithelium remains to be elucidated. Although expression of maspin mRNA is low or absent in most