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Expression and regulation of tumor suppressor gene maspin in human bladder cancer

✍ Scribed by Shuji Sugimoto; Nicolai Maass; Yukie Takimoto; Katsuhiko Sato; Sadatsugu Minei; Ming Zhang; Yutaka Hoshikawa; Klaus-Peter Jünemann; Walter Jonat; Koichi Nagasaki

Book ID
116332902
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
307 KB
Volume
203
Category
Article
ISSN
0304-3835

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Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis; however, its precise role in normal mammary epithelium remains to be elucidated. Although expression of maspin mRNA is low or absent in most