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Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics

✍ Scribed by Zhengguan Yang; Alan S. Waldman; Michael D. Wyatt

Book ID
113489712
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
582 KB
Volume
83
Category
Article
ISSN
0006-2952

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## Abstract Rad51‐catalyzed homologous recombination is an important pathway for repair of DNA double strand breaks and maintenance of genome integrity in vertebrate cells. Five proteins referred to as Rad51 paralogs promote Rad51 activity and are proposed to act at various, and in some cases, mult