Expression of RAD51, BRCA1 and P53 does not correlate with cellular radiosensitivity of normal human fibroblasts
โ Scribed by E. M. Y. Saleh; R. A. E. El-Awady
- Book ID
- 107526417
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 265 KB
- Volume
- 180
- Category
- Article
- ISSN
- 1863-4362
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We introduced the mutant p53 zene (codon 273Ar9-His) into human fibroblasts (SUSM-I ceils) previously immortalized with 4-nitroquinoline I -oxide (4NQO) and obtained 2 clonal cell lines (SUSM-I /p53-I and SUSM-l/p53-6) expressing the mutant p53. Since the genetic background of SUSM-l/p53 is the same