Expression and function of the B and T l
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Noriko Otsuki; Yousuke Kamimura; Masaaki Hashiguchi; Miyuki Azuma
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Article
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2006
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Elsevier Science
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English
β 420 KB
Co-signal receptors provide crucial activating or attenuating signals for T cells. The B and T lymphocyte attenuator (BTLA/CD272) is a third member of co-inhibitory receptors, which belongs to the CD28 immunoglobulin-superfamily. Using monoclonal antibodies (mAbs) against human BTLA, we show that BT