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The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes

✍ Scribed by Eva S.K. Rijkers; Talitha de Ruiter; Ajoeb Baridi; Henrike Veninga; Robert M. Hoek; Linde Meyaard


Book ID
116756674
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
634 KB
Volume
45
Category
Article
ISSN
0161-5890

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Co-signal receptors provide crucial activating or attenuating signals for T cells. The B and T lymphocyte attenuator (BTLA/CD272) is a third member of co-inhibitory receptors, which belongs to the CD28 immunoglobulin-superfamily. Using monoclonal antibodies (mAbs) against human BTLA, we show that BT