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Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production

✍ Scribed by Manabu Kawamoto, Masayoshi Harigai, Masako Hara…


Book ID
120707505
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
895 KB
Volume
8
Category
Article
ISSN
1478-6354

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We describe a patient with systemic lupus erythematosus who, after a disease flare, sequentially produced antibodies to specific Sm polypeptides (demonstrated by counterimmunoelectrophoresis, immunoblotting, and RNA immunoprecipitation) concomitantly with the disappearance of anti-double-stranded DN