Expression and function of CD80 and CD86 costimulator molecules on synovial dendritic cells in chronic arthritis
β Scribed by Kelly L. Summers; John L. O'Donnell; Lisa A. Williams; Derek N. J. Hart
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 529 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
Objective. To assess the expression of important accessory molecules such as CDSO (B7/BB1) and CD54 (intercellular adhesion molecule 1) on potential antigenpresenting cells (APC) in the synovial fluid (SF) of patients with rheumatoid arthritis (RA). Methods. The level of expression of various acces
Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,