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Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection

โœ Scribed by Zaitseva, Marina; Blauvelt, Andrew; Lee, Shirley; Lapham, Cheryl K.; Kiaus-Kovrun, Vera; Mostowski, Howard; Manischewitz, Jody; Golding, Hana


Book ID
109932744
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
731 KB
Volume
3
Category
Article
ISSN
1078-8956

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## Abstract Within the brain, HIVโ€1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in contrast to microglia. We aimed to determine whether chemokine receptors play a role in mediating CD4โ€independent HIVโ€1 entry into astr