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Expression and Activity of the CDK Inhibitor p57Kip2 in Chondrocytes Undergoing Hypertrophic Differentiation

โœ Scribed by Matthew C Stewart; Renata M Kadlcek; Paul D Robbins; James N Macleod; R Tracy Ballock


Book ID
111484973
Publisher
American Society for Bone and Mineral Research
Year
2003
Tongue
English
Weight
714 KB
Volume
19
Category
Article
ISSN
0884-0431

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MyoD induces the expression of p57Kip2 i
โœ Rocco Figliola; Rossella Maione ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 299 KB

## Abstract The myogenic factor MyoD induces the expression of the cdk inhibitor p21 to promote cell cycle withdrawal in differentiating myoblasts. Although the cdk inhibitor p57 is also highly expressed in skeletal muscle and is thought to redundantly control myogenesis, little is known about its