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Dynamic temporal and spatial regulation of the cdk inhibitor p57kip2 during embryo morphogenesis

✍ Scribed by Josh Westbury; Marie Watkins; Anne C. Ferguson-Smith; Janet Smith

Book ID: 118602252
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 787 KB
Volume: 109
Category: Article
ISSN: 0925-4773
DOI: 10.1016/s0925-4773(01)00512-3

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## Abstract The myogenic factor MyoD induces the expression of the cdk inhibitor p21 to promote cell cycle withdrawal in differentiating myoblasts. Although the cdk inhibitor p57 is also highly expressed in skeletal muscle and is thought to redundantly control myogenesis, little is known about its