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A pro-apoptotic effect of the CDK inhibitor p57Kip2 on staurosporine-induced apoptosis in HeLa cells

✍ Scribed by Magnus K.R Samuelsson; Ahmad Pazirandeh; Sam Okret

Book ID
117052379
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
264 KB
Volume
296
Category
Article
ISSN
0006-291X

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MyoD induces the expression of p57Kip2 i
MyoD induces the expression of p57Kip2 in cells lacking p21Cip1/Waf1: Overlapping and distinct functions of the two cdk inhibitors
✍ Rocco Figliola; Rossella Maione πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 299 KB

## Abstract The myogenic factor MyoD induces the expression of the cdk inhibitor p21 to promote cell cycle withdrawal in differentiating myoblasts. Although the cdk inhibitor p57 is also highly expressed in skeletal muscle and is thought to redundantly control myogenesis, little is known about its