Topoisomerase II (TopoII) is a Mg-dependent enzyme involved in topological modifications of DNA that are crucial to the regulation of cell proliferation and possibly differentiation. To investigate the role of Mg availability in the modulation of TopoII in whole cells, we studied enzyme activity and
The effect of staurosporine on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells
β Scribed by Leonard A. Zwelling; Elizabeth Altschuler; Janice Mayes; Michael Hinds; Diana Chan
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 490 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0344-5704
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