Exploring the unfolding of proteins
✍ Scribed by R J Feldmann
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 331 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0263-7855
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Protein unfolding occurs when the balance of forces between the protein's interaction with itself and the protein's interaction with its environment is disrupted. The disruption of this balance of forces may be as simple as a perturbance of the normal water structure around the protein. A decrease i
The position of unfolding curves of oligomeric proteins depends on the protein concentration. The extent of this dependence is analyzed here in terms of the midpoint concentration, i.e., the denaturant concentration at which the fractions of folded and unfolded protein are equal. Reexamination of pu