✦ LIBER ✦

Exploring the Binding Site of the G Protein-Coupled Receptor GPR119 Model using a Pair of Diastereomers with Opposing Action

✍ Scribed by Kotsikorou, Evangelia; Askar, Shane M.

Book ID: 122868339
Publisher: Biophysical Society
Year: 2014
Tongue: English
Weight: 40 KB
Volume: 106
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.2707

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of a second generation agonist

Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile

✍ Graeme Semple; Juerg Lehmann; Amy Wong; Albert Ren; Marc Bruce; Young-Jun Shin; 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 347 KB

ChemInform Abstract: Discovery of Fused

ChemInform Abstract: Discovery of Fused Bicyclic Agonists of the Orphan G-Protein Coupled Receptor GPR119 with in vivo Activity in Rodent Models of Glucose Control.

✍ Graeme Semple; et al. et al. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 26 KB

## Abstract Based on a known lead, a new structural series of agonists of the pancreatic and GI‐expressed orphan G‐protein coupled receptor GPR119 are designed and synthesized.